I.NAN.D (nandrolone decanoate) is an injectable anabolic steroid of the progestin group. It has a pronounced anabolic effect and a very low androgenic effect relative to testosterone. Because I.NAN.D belongs to the progestin group, it binds to progestin receptors and greatly increases prolactin secretion, and because of this, a course of nandrolone always increases prolactin, which should be decreased by prefomimetics such as cabergoline.
Most of the nadrolone converts to dihydronandrolone which is weaker than nandrolone and therefore has a low androgenic activity, but little negative effect on the prostate gland. I.NAN.D affects the reduction of 5-alpha-reductase enzyme activity, which leads to a decrease in DHT levels, which in turn actively affects libido, so nandrolone can negatively affect either, and because of libido and erections (popularly known effect under the name “deca dick”).
I.NAN.D is able to convert to estradiol without the aromatase enzyme, although to a lesser extent than testosterone, but this leads to an increase in estradiol that cannot be reduced by aromatase inhibitors. Also, nandrolone very strongly suppresses the hypothalamic-pituitary-testicular arc, which leads to severe atrophy of the testicles. Post-course therapy after I.NAN.D is longer than after other steroids.
- Anabolic activity: 150%
- Androgenic activity: 30%
- Aromatization: absent, but converted to estradiol without aromatase enzyme
- Progestin activity: present, due to belonging of the drug to the progestin group
- Toxicity: moderate
- Duration of action: depends on the ester
- Increased blood pressure
- Decreased libido, due to increased prolactin
- Gynecomastia (both estrogenic and prolactinic)
- Increased blood pressure.
- Toxic, has a negative effect on the liver.
- Increased LDL.
- Increased red blood cell count and hemoglobin.
Recommended working doses
100-300 mg per week. This dosage, together with testosterone, as it must be present on the course, works and significantly increases muscle mass growth, with minimal side effects.
400 to 600 mg per week. Increasing the dosage beyond 600 mg per week has many side effects, which are difficult to control. It is possible increase of estradiol which cannot be reduced by aromatase inhibitors because nandrolon converts to estradiol without aromatase enzyme. And also a number of side effects related to prolactin.